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BAX 抗体 (AA 41-76)

This anti-BAX antibody is a 兔 多克隆 antibody detecting BAX in WB, IHC 和 FACS. Suitable for 人.
产品编号 ABIN2797999
发货至: 中国

Quick Overview for BAX 抗体 (AA 41-76) (ABIN2797999)

抗原

See all BAX 抗体
BAX (BCL2-Associated X Protein (BAX))

适用

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宿主

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克隆类型

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多克隆

标记

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This BAX antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 41-76

    原理

    Rabbit Anti-Human Bax (BH3 Domain Specific) Antibody

    免疫原

    This Bax antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-76 amino acids from human Bax.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot, Immunohistochemistry, Flow Cytometry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:50-100, FC: 1:10-50Bax Antibody(BH3) with the Bax gene.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.600 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    BAX (BCL2-Associated X Protein (BAX))

    别名

    Bax

    背景

    Target Description: Bax belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bax forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of the Bax gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.

    Gene Symbol: BAX

    分子量

    21184 Da

    基因ID

    581

    UniProt

    Q07812

    途径

    p53 Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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